Experience the gold standard enzyme treatment for dissolving hyaluronic acid fillers. Hylenex can:
Hylenex in Charlotte
Safely dissolve unwanted hyaluronic acid fillers or address related complications. Restore your natural facial contours and symmetry with confidence, knowing you’re supported by a team committed to delivering the outcomes you desire.

Transform Unwanted Results Quickly and Effectively with Hylenex

Correct Overfilled or Uneven Areas
If your fillers haven’t achieved the desired results, Hylenex:
- Dissolves excess filler to restore your natural proportions
- Corrects asymmetries and creates balanced facial contours
- Removes lumps, nodules, or irregularities that may have formed
- Prepares areas for new filler placement with optimal results
Emergency Vascular Occlusion Treatment
For rare, but serious filler complications, Hylenex provides:
- Immediate relief for filler-induced vascular blockage
- Prevention of tissue death when administered within 4-48 hours
- Restoration of blood flow by dissolving fillers to alleviate vessel compression
- The best option for ensuring patient safety during complications


Revision and Enhancement Procedures
Strategic filler dissolution for aesthetic refinement:
- Removes previous filler to restore your natural look
- Addresses bluish discoloration under thin skin
- Eliminates migration or displacement of filler material
- Creates a clean slate for updated aesthetic approaches
Why Hylenex is Your Best Choice for Filler Dissolution in Charlotte
When you need filler correction, understanding your options helps you make the best decision for your safety and results:
Speed and Effectiveness
Unlike waiting over a year for natural dissolution, you’ll see immediate results.
Most patients see significant improvement within 24-48 hours, with complete dissolution typically achieved within two weeks.
Precision and Control
Traditional alternatives, such as massage and heat application, offer little control over the outcome.
Hylenex allows for targeted dissolution exactly where needed, preserving surrounding areas and your natural tissues.
Safe Dissolution
Hylenex represents the purest, safest filler dissolution treatment available.
Unlike animal-derived alternatives, there have been no documented cases of allergy with Hylenex, and it has 100 times the potency of animal-derived alternatives.
Universal Compatibility
Hylenex dissolves all major hyaluronic acid filler brands, though effectiveness may vary based on the filler’s cross-linking and concentration.
Restylane typically responds most readily, followed by RHA and Juvederm products.
Medical Applications Beyond Aesthetics
Hyaluronidase has been used safely in medicine for almost 80 years, with applications in anesthesia, pain management, and fluid administration, demonstrating its proven safety record.
Your Hylenex Experience at Carolina Facial Plastics
Your filler correction journey begins with a thorough assessment to determine the best approach for your specific situation. Our expertise ensures safe, effective treatment customized for your needs, including:
- Comprehensive evaluation of existing filler and desired corrections
- Precise injection technique targeting only the areas that need adjustment
- Immediate effect with results visible within 24-48 hours
- Follow-up care to ensure optimal outcomes and plan any additional treatments

Hylenex FAQ
What is Hylenex and how does it work?
Hylenex is an enzyme that breaks down hyaluronic acid, a common component in many dermal fillers. It is used to dissolve unwanted or incorrectly placed hyaluronic acid fillers quickly and effectively. The enzyme targets the chemical bonds in HA molecules, breaking them into smaller fragments that your body can naturally absorb.
Which fillers can Hylenex dissolve?
Hylenex specifically targets hyaluronic acid fillers like Juvederm, Restylane, and RHA. It does not work on non-HA fillers such as Radiesse, Sculptra, or Bellafill. If you’re unsure about your filler type, our team can help identify what was used and determine the best approach.
How quickly does Hylenex work?
Hyaluronidase has an immediate effect and a half-life of two minutes with a duration of action of 24 to 48 hours. Most patients notice significant improvement within 24-48 hours, with optimal results typically achieved within one week.
Is Hylenex safe for everyone?
There have been no documented cases of allergy with Hylenex (human recombinant rHuPH20), making it significantly safer than animal-derived alternatives. However, Hylenex should not be used in patients with a known hypersensitivity to hyaluronidase or any of its components.
How much Hylenex is needed to dissolve filler?
A consensus opinion in the literature states five units of hyaluronidase is needed to break down 0.1mL of 20mg/mL HA, though this varies based on the filler type, amount, and location. Our team will determine the precise dosage needed for your specific situation.
When can I get new filler after Hylenex treatment?
Wait at least two weeks after Hylenex treatment to ensure the previous filler has completely dissolved and hyaluronidase has been flushed from the injected area before attempting new filler injections. This waiting period ensures optimal results from your new treatment.
What should I expect during recovery?
After Hyaluronidase, it is common to have some localized swelling that should subside within 48-72 hours. Bruising may also occur and should subside in a few days (up to a week). Makeup and skincare can be applied 24 hours afterwards.
Can Hylenex be used during pregnancy or breastfeeding?
No Hyaluronidase, Hylenex, is not recommended when pregnant or breastfeeding. We recommend waiting until after pregnancy and nursing to pursue any aesthetic treatments.
What areas can be treated with Hylenex?
Temple, under eye, cheeks, chin, jawline, and lips are all common treatment areas. Hylenex can be used anywhere hyaluronic acid filler has been placed, making it versatile for full-face corrections.
How many Hylenex treatments will I need?
Most patients achieve their desired results with a single treatment. However, in some cases, more than one session of hyaluronidase may be required to achieve the desired correction, especially for larger amounts of filler or when multiple areas need adjustment.
Is there any downtime with Hylenex?
Pain is minimal, and soreness post-treatment can be minimized with ice and Tylenol. Most patients return to normal activities immediately, though avoid strenuous exercise, ibuprofen, aspirin, or alcohol for 24 hours as this might increase your risk of bruising.
What makes Carolina Facial Plastics the right choice for Hylenex treatment?
Our expert providers received extensive training under double board-certified facial plastic surgeon Dr. Jonathan Kulbersh, whose Beverly Hills training and mentorship equips your specialist with a deep understanding of facial anatomy, aesthetics, and the latest techniques for safer, more natural-looking results.